Given the need to comply with product safety requirements and statutory regulations, the pharmaceuticals sector is an industry that demands high production as well as R&D plant and equipment standards. And that certainly includes feeding technology. In addition to absolute precision and ease of cleaning, flexibility is called for especially when formulations have to be adapted and ingredients have to be modified. The bulk ingredients used can vary between powders, powder mixes, pellets and liquids – each exhibiting different flow characteristics from free-flowing to bridging. Kubota Brabender Technologie meets these challenges by providing specially tailored feeders.
Our Hygienic Design equipment also complies with GMP Standards (EU) and FDA Guidelines (USA) that apply to the pharmaceuticals industry.
- Single screw feeder (DSR)
- Twin screw feeder (DDSR)
- Small-size twin screw feeder MiniTwin
Further information worth knowing about our bulk ingredient solutions for the pharmaceutical industry (PDF)
湿法制粒
湿法制粒是指药物粉末中加入液体粘合剂,靠粘合剂的架桥或粘结作用使粉末聚结在一起而制备颗粒的方法。液体中含有溶剂，可以通过干燥去除。布拉本达技术公司为这些应用提供精确的计量。
可能的馈线
- DDSR, DSR, MiniTwin
混合
布拉本达技术公司计量秤可使片剂生产中使用的粉末在混合和压制成片剂之前得到精确的喂料。通常情况下，需要多台计量秤用于精确跟踪片剂配方。
可能的馈线
- DDSR, DSR, MiniTwin
压片
片剂不仅仅是压缩的粉末。它由许多成分组成，包括活性和非活性成分，通常具有不同的层次。这些层通常由涂层隔离。例如，这些涂层使片剂更容易吞咽或允许活性成分的定时释放。无论采用何种技术，精确遵循配方、确保完整的审计跟踪、遵守适当的法规并满足一般的生产实践是绝对必要的。
可能的馈线
- DDSR, DSR, MiniTwin
其他
以牙膏为例，牙膏中含有许多不同的成分，如磨料、发泡剂、调味剂、香精、着色剂、其他添加剂和预防蛀牙的活性成分等。这些成分都是在搅拌机中加工而成的，必须由失重式计量秤精确地喂料。
可能的馈线
- DDSR, DSR, MiniTwin
Interesting articles on feeding in the pharmaceutical industry
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